INTRODUCTION TO PHARMACOLOGY and therapeutics

Course: INTRODUCTION TO PHARMACOLOGY and therapeutics

CHAPTER ONE

TERMINOLOGIES AND IMPORTANCE OF PHARMACOLOGY

TERMINOLOGIES

• PHARMACOLOGY:- Is the study of interaction between chemicals and living systems.

Is a branch of biology concerned with the study of drug actions?

Is from the Greek word pharmacos – drugs, logos-study

• DRUG:- A drug is broadly defined as any chemical agent that affects biological systems.

SUB-DIVISION OF PHARMACOLOGY

• PHARMACOLKNETICS- Describes “what the body does to the drug. This includes topics such as absorption, distribution, metabolism and excretion (ADME) of drugs. 

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Drug at site of administration 

                               Absorption            input 

                Drug in plasma

Drug in tissues

Metabolism

Metabolites in tissue

Elimination              output 

Drug and/or metabolite(s) in Urine, bile or feaces     Figure 1:1